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The Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg, Germany, is an interdisciplinary research institution that conducts basic research in two key areas of modern biology: immunobiology and epigenetics. Central questions address the molecular basis of cell type identities, as they are regulated during immune cell differentiation, metabolic response, and epigenetic chromatin adaptation.

We are looking for a

Postdoc (m/f/div) in Bioinformatics

The Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany, is offering a Post­doctoral Position in bioinformatics in the Department of Chromatin Regulation (Head: Prof. Dr. Asifa Akhtar / max.mpg.de/sites/mpi-ie/Research-Groups/Lab-Akhtar).

The lab generates large quantities of deep sequencing datasets, including RNA-seq, ChIP-seq, ATAC-seq, and Nanopore long-read sequencing, which we analyze using a combination of adaptation of existing bioinformatic tools and development of new analysis tools. Members of the lab also contributed to the deepTools2 suite (Ramírez et al 2016 Nucleic Acids Research) and snakePipes package (Bhardwaj et al 2019 Bioinformatics) developed by the bio­infor­matics facility headed by Dr. Thomas Manke.

The position is available for an initial two-year appointment with the possibility of extension.


Aufgaben

We are looking for an ambitious, highly motivated, science-driven, and experienced bioinformatician to join our team to unravel the molecular mechanisms that regulate gene expression. You will work closely together with wet lab scientists in the analysis of a broad range of NGS datasets. You will contribute your expertise in bioinformatics to advise wet lab scientists on design, implementation, troubleshooting, and analysis of sequencing-based experiments.


Profil
  • Academic degree in computer science or in the natural sciences and a doctorate in the field of natural science or bioinformatics
  • Proficiency in programming in R and/or Python, Unix / Shell scripts as well as the ability to build new tailored pipelines are prerequisites for this position
  • Candidates should have at least three years of proven experience in analyses of omics data (such as ChIP-seq, RNA-seq, ATAC-seq, bisulfite sequencing and/or HiC)
  • Prior experience with analysis of single-cell RNA / ATAC / Multiome sequencing and/or long-read sequencing (e.g. Oxford Nanopore) data would also be beneficial
  • Candidates must have a strong publication record, have the ability to work well in a team, and possess excellent communication skills
  • Experience with HPC clusters and Snakemake would be advantageous
  • Experience in integration of genome-wide data with proteomics and/or metabolomics data would be a bonus
  • Experience in the supervision of graduate students would be an asset

Wir bieten

Located in a region that connects Germany, France, and Switzerland, our institute offers an inter­national research environment with outstanding infrastructure facilities and a positive working atmosphere that places a high value on work-life balance.

  • Payment according to TVöD up to a maximum of E 13 if the collectively agreed and personal requirements are fulfilled
  • Social benefits in line with public service (VBL)
  • Additional performance-related remuneration component
  • Professional training and development opportunities
  • Good public transport connections and subsidy for job ticket
  • Challenging work in a modern working environment
  • Mobile working at a location of your choice within Germany is possible up to a maximum of 40% of the regular weekly working hours in justified cases
  • Family-friendly offers (affiliated day care center at the institute, parent-child room, breastfeeding room)

We value and promote diversity, inclusion, and equal opportunities, so we welcome applications from all backgrounds. We particularly welcome applications from severely disabled people. We would also like to increase the proportion of women in areas where they are underrepresented and therefore expressly encourage women to apply.